See main article: 2010 St. Petersburg Open. Colin Fleming and Ken Skupski were the defending champions, but lost to Filip Polášek and Igor Zelenay in the first round.
Daniele Bracciali and Potito Starace won the final against Rohan Bopanna and Aisam-ul-Haq Qureshi 7–6(8–6), 7–6(7–5).