| Competition: | sanfl |
| Year: | 2010 |
| Teams: | 9 |
| Count: | 9 |
| Mpcount: | 10 |
| Matches: | 96 |
| Attendance: | 343891 |
| Highattend: | 34,355 (Grand Final, vs.) |
| Top Goal Scorer: | Todd Grima (56 goals) |
| Magarey Medal: | James Allan (22 votes) |
| Prevseason: | 2009 |
| Nextseason: | 2011 |
The 2010 South Australian National Football League season was the 131st season of the top-level Australian rules football competition in South Australia.