The 2010 Porsche Tennis Grand Prix was a women's tennis tournament played on indoor clay courts. It was the 33rd edition of the Porsche Tennis Grand Prix, and was part of the Premier tournaments of the 2010 WTA Tour. It took place at the Porsche Arena in Stuttgart, Germany, from 24 April until 2 May 2010. Seven of the top ten ranked women and four former world number ones participated in the event. Justine Henin won the singles title.
| Player | Nationality | Ranking* | Seeding | |
|---|---|---|---|---|
| Caroline Wozniacki | Denmark | 2 | 1 | |
| Dinara Safina |  Russia | 3 | 2 | |
| Svetlana Kuznetsova | Russia | 5 | 3 | |
| Jelena Janković |  Serbia | 7 | 4 | |
| Agnieszka Radwańska |  Poland | 8 | 5 | |
| Victoria Azarenka |  Belarus | 9 | 6 | |
| Samantha Stosur |  Australia | 10 | 7 | |
| Yanina Wickmayer |  Belgium | 12 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
Margalita Chakhnashvili (as a Lucky loser) Anna Lapushchenkova Tatiana Poutchek
Selima SfarSee main article: 2010 Porsche Tennis Grand Prix – Singles. Justine Henin defeated Samantha Stosur, 6–4, 2–6, 6–1
See main article: 2010 Porsche Tennis Grand Prix - Doubles. 
Gisela Dulko / 
Flavia Pennetta defeated 
Květa Peschke / Katarina Srebotnik, 3–6, 7–6(7–3), [10–5]