| Competition: | Primera División |
| Season: | 2010 |
| Relegated: | Sport Colombia Trinidense |
| Continentalcup1: | Copa Libertadores |
| Continentalcup1 Qualifiers: | Libertad Guaraní Cerro Porteño |
| Continentalcup2: | Copa Sudamericana |
| Continentalcup2 Qualifiers: | Libertad Nacional Olimpia |
| League Topscorer: | Apertura: Rodrigo Teixeira Pablo Zeballos (16 goals each) Clausura: Juan Carlos Ferreyra Roberto Nanni (12 goals each) |
| Matches: | 264 |
| Total Goals: | 667 |
| Prevseason: | 2009 |
| Nextseason: | 2011 |
The 2010 División Profesional season (officially the 2010 Copa TIGO- Visión Banco for sponsorship reasons) was the 76th season of top-flight professional football in Paraguay. It was the third season in which a champion was crowned for each tournament.
| Team | Home city | Stadium | Capacity | |
|---|---|---|---|---|
| 28,000 | ||||
| 32,000 | ||||
| 6,000 | ||||
| 10,000 | ||||
| 4,000 | ||||
| 15,000 | ||||
| 5,000 | ||||
| 5,000 | ||||
| 7,000 | ||||
| 25,000 | ||||
| 3,000 | ||||
| 7,000 |
The Campeonato de Apertura, also the Torneo TIGO Apertura for sponsorship reasons, is the first championship of the season. It began on January 30 and ended on May 30.
| Player | Nationality | Club | Goals | ||
|---|---|---|---|---|---|
| align=center rowspan=2 | 1 | Rodrigo Teixeira |  Brazil | Guaraní | 16 |
| Pablo Zeballos | Cerro Porteño | 16 | |||
| align=center rowspan=2 | 3 | Guillermo Beltrán | Nacional | 8 | |
| Nelson Cuevas | Olimpia | 8 | |||
| align=center rowspan=5 | 5 | Roberto Acuña | Rubio Ñú | 7 | |
| Miguel Cuéllar | 3 de Febrero | 7 | |||
| Francisco Esteche | Sportivo Luqueño | 7 | |||
| Jonathan Fabbro | Guaraní | 7 | |||
| Roberto Gamarra | Libertad | 7 | |||
| align=center rowspan=2 | 10 | Diego Alfonso | Tacuary | 6 | |
| Julio dos Santos | Cerro Porteño | 6 |
The Campeonato de Clausura, also the Torneo Tigo Clausura for sponsorship reasons, is the second championship of the season. It began on July 16 and ended December 12.
| Player | Nationality | Club | Goals | ||
|---|---|---|---|---|---|
| align=center rowspan=2 | 1 | Juan Carlos Ferreyra |  Argentina | Olimpia | 12 |
| Roberto Nanni | Argentina | Cerro Porteño | 12 | ||
| 3 | Ángel Orué | Libertad | 9 | ||
| align=center rowspan=2 | 4 | Ariel Bogado | Nacional | 8 | |
| Manuel Maciel | Libertad | 8 | |||
| align=center rowspan=3 | 6 | Néstor Camacho | Rubio Ñú | 6 | |
| Jonathan Fabbro | Guaraní | 6 | |||
| Pablo Zeballos | Cerro Porteño | 6 | |||
| align=center rowspan=6 | 9 | Julián Benítez | Guaraní | 5 | |
| Nery Cardozo | Rubio Ñú | 5 | |||
| Hugo Luzardi | Sportivo Luqueño | 5 | |||
| Jorge Núñez | Cerro Porteño | 5 | |||
| Luis Ovelar | Sportivo Luqueño | 5 | |||
| Sergio Samudio | 3 de Febrero | 5 | |||
The two tournament champions earn the Paraguay 1 and Paraguay 2 berths in the Second Stage of the 2011 Copa Libertadores. All remaining international qualification will be determined through a season-wide aggregate table. The Paraguay 3 in the 2011 Copa Libertadores berth goes to the best-placed non-champion. For the 2011 Copa Sudamericana, the Paraguay 1 berth goes to the highest placed champion. Paraguay 2 and Paraguay 3 will go to the highest placed teams who have not qualified to an international tournament.
Relegations is determined at the end of the season by computing an average (es|promedio) of the number of points earned per game over the past three seasons. The two teams with the lowest average is relegated to the División Intermedia for the following season.
| width=28 | Pos ! | width=185 | Team ! | width=50 | '08 Pts ! | width=50 | '09 Pts ! | width=50 | '10 Pts ! | width=50 | Total Pts ! | width=50 | Total Pld ! | width=50 | Avg ! | Relegation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Libertad | 101 | 82 | 87 | 270 | 132 | ||||||||||
| 2 | Cerro Porteño | 76 | 81 | 91 | 247 | 132 | ||||||||||
| 3 | Guaraní | 79 | 67 | 85 | 231 | 132 | ||||||||||
| 4 | Nacional | 77 | 77 | 77 | 231 | 132 | ||||||||||
| 5 | Olimpia | 54 | 70 | 71 | 195 | 132 | ||||||||||
| 6 | Rubio Ñú | 0 | 63 | 66 | 129 | 88 | ||||||||||
| 7 | Sol de América | 63 | 50 | 45 | 158 | 132 | ||||||||||
| 8 | 52 | 64 | 37 | 155 | 132 | |||||||||||
| 9 | Sportivo Luqueño | 49 | 51 | 42 | 142 | 132 | ||||||||||
| 10 | 3 de Febrero | 51 | 43 | 38 | 132 | 132 | ||||||||||
| 11 | 0 | 0 | 41 | 41 | 44 | Relegated to the División Intermedia | ||||||||||
| 12 | Sportivo Trinidense | 0 | 0 | 37 | 37 | 44 |