The 2010 Open Prévadiès Saint–Brieuc was a professional tennis tournament played on outdoor red clay courts. It was part of the 2010 ATP Challenger Tour. It took place in Saint-Brieuc, France between 29 March and 4 April 2010.
| Nationality | Player | Ranking* | Seeding | |
|---|---|---|---|---|
 Spain | Marcel Granollers | 92 | 1 | |
 Russian Federation | Teymuraz Gabashvili | 112 | 2 | |
 France | Josselin Ouanna | 115 | 3 | |
 Poland | Michał Przysiężny | 130 | 4 | |
| Spain | Rubén Ramírez Hidalgo | 131 | 5 | |
| France | ||||
 Belgium | Kristof Vliegen | 150 | 7 | |
 Czech Republic | Jan Hernych | 151 | 8 | |
| France | Thierry Ascione | 162 | 9 |
The following players received wildcards into the singles main draw:
Charles-Antoine Brézac Romain Jouan Benoît Paire Olivier PatienceThe following players received entry from the qualifying draw:
Laurynas Grigelis
Samuel Groth Florian Reynet Charles RocheSee main article: 2010 Open Prévadiès Saint–Brieuc – Singles. Michał Przysiężny def. Rubén Ramírez Hidalgo, 4–6, 6–2, 6–3
See main article: 2010 Open Prévadiès Saint–Brieuc – Doubles. 
Uladzimir Ignatik / David Marrero def. 
Brian Battistone / Ryler DeHeart, 4–6, 6–4, [10–5]