The 2010 Open 13 is a men's tennis tournament played on indoor hard courts. It was the 17th edition of the Open 13, and is part of the International Series of the 2010 ATP World Tour. It took place at the Palais des Sports in Marseille, France, from February 15 through February 21, 2010.
It was also one of the few ATP tournaments to have been won only by European players, with France with 5 (Guy Forget, Fabrice Santoro, Arnaud Clément, Gilles Simon, and this year's defending champion Jo-Wilfried Tsonga), Sweden with 4 (Thomas Enqvist, Joachim Johansson), Switzerland with 4 (Marc Rosset, Roger Federer), Germany with 1 (Boris Becker), Russia with 1 (Yevgeny Kafelnikov), Slovakia with 1 (Dominik Hrbatý), and Great Britain with 1 (Andy Murray).
The singles draw feature ATP No. 8, 2009 French Open finalist Robin Söderling and defending champion Jo-Wilfried Tsonga. Other players include Gaël Monfils, Gilles Simon, Tommy Robredo, Mikhail Youzhny, Marcos Baghdatis and Julien Benneteau. The previous top two seeds here were Andy Murray and Juan Martín del Potro, but both had pulled out of the tournament earlier.
| Player | Nationality | Ranking* | Seeding | |
|---|---|---|---|---|
| Robin Söderling |  Sweden | 8 | 1 | |
| Jo-Wilfried Tsonga |  France | 9 | 2 | |
| Gaël Monfils | France | 13 | 3 | |
| Tommy Robredo |  Spain | 15 | 4 | |
| Gilles Simon | France | 16 | 5 | |
| Mikhail Youzhny |  Russia | 20 | 6 | |
| Marcos Baghdatis |  Cyprus | 36 | 7 | |
| Julien Benneteau | France | 38 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
The following players received entry as a lucky loser from the qualifying draw:
See main article: 2010 Open 13 – Singles. Michaël Llodra defeated Julien Benneteau, 6–3, 6–4
See main article: 2010 Open 13 – Doubles. Julien Benneteau / Michaël Llodra defeated 
Julian Knowle / Robert Lindstedt, 6–3, 6–4
