| Date: | August 2 – August 8 |
| Edition: | 6th (men) 9th (women) |
| Category: | ATP Challenger Tour ITF Women's Circuit |
| Prize Money: | (men) (women) |
| Surface: | Hard – outdoors |
| Location: | West Vancouver, British Columbia, Canada |
| Venue: | Hollyburn Country Club |
| Champms: |  Dudi Sela |
| Champws: |  Jelena Dokić |
| Champmd: | Treat Conrad Huey /  Dominic Inglot |
| Champwd: | Chang Kai-chen /  Heidi El Tabakh |
| Main Name: | Vancouver Open |
The 2010 Odlum Brown Vancouver Open was a professional tennis tournament played on outdoor hard courts. It was the 6th edition, for men, and 9th edition, for women, of the tournament and part of the 2010 ATP Challenger Tour and the 2010 ITF Women's Circuit, offering totals of $100,000, for men, and $75,000, for women, in prize money. It took place in West Vancouver, British Columbia, Canada between August 2 and August 8, 2010.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Taylor Dent | 84 | 1 | ||
| Tobias Kamke | 102 | 2 | ||
| Israel | Dudi Sela | 104 | 3 | |
 Lithuania | Ričardas Berankis | 131 | 4 | |
 Serbia | Ilija Bozoljac | 135 | 5 | |
| Jesse Levine | 152 | 6 | ||
| Robert Kendrick | 155 | 7 | ||
| Jesse Witten | 169 | 7 |
The following players received wildcards into the singles main draw:
The following players entered the singles main draw with a special exempt:
The following players received entry from the qualifying draw:
See main article: article and 2010 Odlum Brown Vancouver Open – Men's singles. Dudi Sela def. Ričardas Berankis, 7–5, 6–2
See main article: article and 2010 Odlum Brown Vancouver Open – Women's singles. Jelena Dokić def. 
Virginie Razzano, 6–1, 6–4
See main article: article and 2010 Odlum Brown Vancouver Open – Men's doubles. Treat Conrad Huey / Dominic Inglot def. 
Ryan Harrison / Jesse Levine, 6–4, 7–5
See main article: article and 2010 Odlum Brown Vancouver Open – Women's doubles. Chang Kai-chen / Heidi El Tabakh def. Irina Falconi / Amanda Fink, 3–6, 6–3, [10–4]