| Gender: | Women's |
| Year: | 2010 |
| Division: | II |
| Teams: | 64 |
| Finalfourcity: | St. Joseph, MO |
| Champions: | Emporia State Lady Hornets |
| Titlecount: | 1st |
| Runnerup: | Fort Lewis Skyhawks |
| Gamecount: | 1st |
| Semifinal1: | Franklin Pierce Ravens |
| Finalfourcount: | 2nd |
| Semifinal2: | Gannon Golden Knights |
| Finalfourcount2: | 1st |
| Coach: | Brandon Schneider |
| Coachcount: | 1st |
| Mop: | Alli Volkens |
| Mopteam: | Emporia State |
The 2010 NCAA Division II women's basketball tournament was the 29th annual tournament hosted by the NCAA to determine the national champion of Division II women's collegiate basketball in the United States.[1]
Emporia State defeated Fort Lewis in the championship game, 65–53, to claim the Lady Hornets' first NCAA Division II national title.
The championship rounds were contested at the St. Joseph Civic Arena in St. Joseph, Missouri.
^ California, Pennsylvania Location: Hamer Hall Host: California University of Pennsylvania
~ Erie, Pennsylvania Location: Hammermill Center Host: Gannon University
Location: Horne Arena Host: Lander University
Location: First United Bank Center Host: West Texas A&M University
Location: SDC Gymnasium Host: Michigan Technological University
Location: Fitchburg State Recreation Center Host: Franklin Pierce College
Location: Tucker Coliseum Host: Arkansas Tech University
Location: Whalen Gymnasium Host: Fort Lewis College
Location: Royal Brougham Pavilion Host: Seattle Pacific University
Location: St. Joseph Civic Arena Host: Missouri Western State University