| Gender: | Women's |
| Year: | 2010 |
| Division: | III |
| Teams: | 64 |
| Finalfourarena: | Shirk Center |
| Finalfourcity: | Bloomington, Illinois |
| Champions: | WashU Bears |
| Titlecount: | 5th |
| Runnerup: | Hope Flying Dutchmen |
| Gamecount: | 2nd |
| Thirdplace: | Amherst Lord Jeffs |
| Finalfourcount: | 2nd |
| Fourthplace: | Rochester Yellowjackets |
| Finalfourcount2: | 3rd |
| Coach: | Nancy Fahey |
| Coachcount: | 5th |
| Mop: | Jaimie McFarlin |
| Mopteam: | Washington University in St. Louis |
| Attendance: | 27490 |
The 2010 NCAA Division III women's basketball tournament was the 29th annual tournament hosted by the NCAA to determine the national champion of Division III women's collegiate basketball in the United States.[1]
Washington University in St. Louis defeated Hope College in the championship game, 65–59, to claim the Bears' fifth Division III national title.
The championship rounds were hosted by Illinois Wesleyan University at the Shirk Center in Bloomington, Illinois.