| Mode: | football |
| Year: | 2010 |
| Team: | Morehead State Eagles |
| Conference: | Pioneer Football League |
| Short Conf: | PFL |
| Record: | 5–6 |
| Conf Record: | 4–4 |
| Head Coach: | Matt Ballard |
| Hc Year: | 17th |
| Stadium: | Jayne Stadium |
The 2010 Morehead State Eagles football team represented Morehead State University in the 2010 NCAA Division I FCS football season as a member of the Pioneer Football League (PFL). The Eagles were led by 17th-year head coach Matt Ballard and played their home games at Jayne Stadium. They finished the season 5–6, 4–4 in PFL play.