| Champ: |  Svetlana Kuznetsova |
| Runner: |  Agnieszka Radwańska |
| Score: | 6–4, 6–7(7–9), 6–3 |
| Draw: | 30 |
| Seeds: | 8 |
| Type: | women |
| Before Year: | 2007 |
| Before Name: | Acura Classic |
See main article: 2010 Mercury Insurance Open. Svetlana Kuznetsova defeated Agnieszka Radwańska 6–4, 6–7(7–9), 6–3 in the final.
The top two seeds receive a bye into the second round.
