| Champ: | Izak van der Merwe |
| Runner: |  Ricardo Mello |
| Score: | 7–6(6), 6–3 |
| Type: | singles doubles |
See main article: 2010 MasterCard Tennis Cup. Horacio Zeballos won last year's edition, but decided not to participate this year.
Izak van der Merwe won the singles title, defeating Ricardo Mello 7–6(6), 6–3 in the finals.