| Election Name: | 2010 Massachusetts Senate election |
| Country: | Massachusetts |
| Type: | legislative |
| Ongoing: | no |
| Previous Election: | 2008 Massachusetts Senate election |
| Previous Year: | 2008 |
| Next Election: | 2012 Massachusetts Senate election |
| Next Year: | 2012 |
| Seats For Election: | All 40 seats in the Massachusetts Senate |
| Majority Seats: | 21 |
| Election Date: | November 2, 2010 |
| Leader1: | Therese Murray |
| Party1: | Massachusetts Democratic Party |
| Leader Since1: | March 21, 2007 |
| Leaders Seat1: | Plymouth and Barnstable |
| Last Election1: | 35 seats |
| Seats1: | 36 |
| Seat Change1: | 1 |
| Leader2: | Richard Tisei (retired) |
| Party2: | Massachusetts Republican Party |
| Leader Since2: | January 3, 2007 |
| Leaders Seat2: | Middlesex and Essex |
| Last Election2: | 5 seats |
| Seats Needed2: | 14 |
| Seats2: | 4 |
| Seat Change2: | 1 |
| Map Size: | 350px |
| President | |
| Before Election: | Therese Murray |
| Before Party: | Massachusetts Democratic Party |
| After Election: | Therese Murray |
| After Party: | Massachusetts Democratic Party |
In the elections to the Massachusetts State Senate in 2010, the Democrats continued their dominance, winning 36 seats against 4 seats for the Republicans.
| District | Incumbent | Party | First elected | Result | Candidates | ||
|---|---|---|---|---|---|---|---|
| Berkshire, Hampshire, and Franklin | Benjamin Downing | Democratic | 2006 | Re-elected | Benjamin Downing (D) unopposed | ||
| Bristol and Norfolk | James Timilty | Democratic | 2004 | Re-elected | James Timilty (D) unopposed | ||
| 1st Bristol and Plymouth | Joan Menard | Democratic | 2000 | Retired Democratic hold | Michael Rodrigues (D) 62.16% Derek Maksy (R) 37.84% | ||
| 2nd Bristol and Plymouth | Mark Montigny | Democratic | 1992 | Re-elected | Mark Montigny (D) unopposed | ||
| Cape and Islands | Robert O'Leary | Democratic | 2000 | Retired to run for 10th Congressional District Democratic hold | Dan Wolf (D) 57.45% James Crocker (R) 42.55% | ||
| 1st Essex | Steven Baddour | Democratic | 2002 | Re-elected | Steven Baddour (D) unopposed | ||
| 2nd Essex | Frederick Berry | Democratic | 1982 | Re-elected | Frederick Berry (D) 61.51% Richard Jolitz (R) 31.47% Matthew Fraser (I) 7.02% | ||
| 1st Essex and Middlesex | Bruce Tarr | Republican | 1994 | Re-elected | Bruce Tarr (R) unopposed |