The 2010 Golden Horses Health Sanctuary Malaysian Open was a tennis tournament played on outdoor hard courts. It was the inaugural edition of the Malaysian Open and was an International tournament on the WTA Tour. The event took place from February 22 to February 28 at the Bukit Kiara Equestrian and Country Resort.
The event was headlined by the participation of World No. 7 and Olympic champion Elena Dementieva in the main draw. Other participants include recent Australian Open semi-finalists, World No. 10 Li Na and World No. 20 Zheng Jie and last years Wimbledon quarter-finalist and Family Circle Cup champion, Sabine Lisicki.
See main article: 2010 Malaysian Open – Singles. 
Alisa Kleybanova defeated Elena Dementieva 6–3, 6–2[1]
See main article: 2010 Malaysian Open – Doubles. Chan Yung-jan / 
Zheng Jie defeated 
Anastasia Rodionova / Arina Rodionova 6–7(4–7), 6–2, [10–7]
| Country | Player | Ranking1 | Seeding | |
|---|---|---|---|---|
| Russian Federation | Elena Dementieva | 7 | 1 | |
| China | Li Na | 10 | 2 | |
| China | Zheng Jie | 20 | 3 | |
| Russian Federation | Alisa Kleybanova | 31 | 4 | |
 Hungary | Melinda Czink | 44 | 5 | |
 Austria | Sybille Bammer | 50 | 6 | |
 Slovakia | Magdaléna Rybáriková | 53 | 7 | |
 Belarus | Olga Govortsova | 56 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
