The 2010 MPS Group Championships was a women's tennis tournament played on outdoor clay courts. It was the 31st edition of the MPS Group Championships and the second held in its new location, and was part of the International series of the 2010 WTA Tour. It took place at the Sawgrass Country Club in Ponte Vedra Beach, Florida, United States from April 5 through April 11, 2010.
The tournament was headlined by world no. 2 Caroline Wozniacki, 2010 Moorilla Hobart International champion Alyona Bondarenko, 2008 finalist Dominika Cibulková, and 2010 Monterrey Open champion Anastasia Pavlyuchenkova.
| Athlete | Nationality | Ranking* | Seeding | |
|---|---|---|---|---|
| Caroline Wozniacki | Denmark | 2 | 1 | |
| Alyona Bondarenko |  Ukraine | 25 | 2 | |
| Dominika Cibulková |  Slovakia | 28 | 3 | |
| Elena Vesnina |  Russia | 34 | 4 | |
| Anastasia Pavlyuchenkova | Russia | 35 | 5 | |
| Aleksandra Wozniak |  Canada | 38 | 6 | |
| Virginie Razzano |  France | 39 | 7 | |
| Melanie Oudin |  United States | 42 | 8 |
The following players received wildcards into the main draw:
The following players received entry via qualifying:
See main article: 2010 MPS Group Championships – Singles. Caroline Wozniacki defeated 
Olga Govortsova, 6–2, 7–5
See main article: 2010 MPS Group Championships – Doubles. Bethanie Mattek-Sands / 
Yan Zi defeated Chuang Chia-jung / Peng Shuai, 4–6, 6–4, [10–8]
