| Competition: | League of Ireland Premier Division |
| Season: | 2010 |
| Matches: | 180 |
| Total Goals: | 479 |
| Winners: | Shamrock Rovers (16th title) |
| Continentalcup1: | UEFA Champions League |
| Continentalcup1 Qualifiers: | Shamrock Rovers |
| Continentalcup2: | UEFA Europa League |
| Continentalcup2 Qualifiers: | Bohemians Sligo Rovers St. Patrick's Athletic |
| Continentalcup3: | Setanta Cup |
| League Topscorer: | Gary Twigg 20 |
| Longest Wins: | Shamrock Rovers (6) |
| Longest Unbeaten: | Shamrock Rovers (17) |
| Longest Losses: | Drogheda United (5) |
| Highest Attendance: | Shamrock Rovers–St. Patrick's Athletic (5500) |
| Lowest Attendance: | Bray Wanderers–Sligo Rovers (300) |
| Average Attendance: | 1,657 |
| Prevseason: | 2009 |
| Nextseason: | 2011 |
The 2010 League of Ireland Premier Division was the 26th season of the League of Ireland Premier Division. The division was made up of 10 teams. Shamrock Rovers were champions while Bohemians finished as runners-up.
Airtricity were announced as the new main sponsor for the League of Ireland on 26 February.[2] [3] The prize fund for the season was set at €911,000.[4] [5] The 2010 Premier Division featured 10 clubs. The regular season began on 5 March and concluded on 29 October. Each team played every other team four times, totalling 36 matches.[6] On the final day of the season, Shamrock Rovers won the title with a 2–2 draw away to Bray Wanderers.[7] [8] Second placed Bohemians finished level on points with Rovers but lost out on goal difference.[9] [10]
| Rank | Scorer | Team | Goals |
|---|---|---|---|
| 1 | Gary Twigg | Shamrock Rovers[11] | 20 |
| 2 |  Pádraig Amond | Sligo Rovers | 17 |
| 3 | Ciarán Kilduff | UCD | 15 |
| 4 | Jake Kelly | Bray Wanderers | 14 |
| 5 | Jason Byrne | Bohemians | 12 |
 Fahrudin Kuduzović | Dundalk | 12 |
The eighth and ninth placed teams from the Premier Division, Galway United and Bray Wanderers, played off after the regular season was completed. The winner would retain a place in the 2011 Premier Division. The loser would play off against the winner of the 2010 First Division play off. The winner of this match would also gain a place in the 2010 Premier Division.