| Team: | La Crosse Spartans |
| Year: | 2010 |
| Record: | 3-11 |
| Division Place: | 4th Central North |
| Coach: | Gilbert Brown |
| General Manager: | Chris Kokalis |
| Owner: | Chris Kokalis |
| Stadium: | La Crosse Center 300 Harbor View Plaza La Crosse, WI 54601 |
| Playoffs: | did not qualify |
| No Prevseason: | true |
The La Crosse Spartans season was the team's first season as a football franchise and first in the Indoor Football League (IFL). One of twenty-five teams competing in the IFL for the 2010 season, the Spartans were members of the Central North Division of the United Conference. The team played their home games at the La Crosse Center in La Crosse, Wisconsin.
| Week | Day | Date | Kickoff | Opponent | Results | Location | |||
|---|---|---|---|---|---|---|---|---|---|
| Final Score | Team Record | ||||||||
| 1 | Friday | January 29 | 7:30pm | Family Night Scrimmage | align="center" | --- | align="center" | --- | La Crosse Center |
| 2 | Sunday | February 21 | 3:00pm | Green Bay Blizzard | L 11-14 | align="center" | --- | La Crosse Center | |
| Week | Day | Date | Kickoff | Opponent | Results | Location | ||
|---|---|---|---|---|---|---|---|---|
| Final Score | Team Record | |||||||
| 1 | Friday | February 26 | 7:05pm | at Wichita Wild | L 20-57 | 0-1 | Hartman Arena | |
| 2 | colSpan=7 align="center" | Bye | ||||||
| 3 | colSpan=7 align="center" | Bye | ||||||
| 4 | Friday | March 19 | 7:10pm | at Green Bay Blizzard | L 12-48 | 0-2 | Resch Center | |
| 5 | Sunday | March 28 | 3:05pm | at Sioux Falls Storm | L 13-45 | 0-3 | Sioux Falls Arena | |
| 6 | Saturday | April 3 | 7:30pm | Omaha Beef | L 27-37 | 0-4 | La Crosse Center | |
| 7 | Sunday | April 11 | 3:00pm | Green Bay Blizzard | L 30-43 | 0-5 | La Crosse Center | |
| 8 | Sunday | April 18 | 7:05pm | Sioux City Bandits | L 20-28 | 0-6 | La Crosse Center | |
| 9 | Friday | April 23 | 7:30pm | West Michigan ThunderHawks | L 58-65 | 0-7 | La Crosse Center | |
| 10 | Friday | April 30 | 7:30pm | Chicago Slaughter | W 35-29 | 1-7 | La Crosse Center | |
| 11 | Saturday | May 8 | 7:05pm | at Bloomington Extreme | L 18-54 | 1-8 | U.S. Cellular Coliseum | |
| 12 | colSpan=7 align="center" | Bye | ||||||
| 13 | Friday | May 21 | 7:30pm | Bloomington Extreme | L 37-40 | 1-9 | La Crosse Center | |
| 14 | Sunday | May 30 | 5:05pm | at Alaska Wild | W 1-0 (forfeit) | 2-9 | Sullivan Arena | |
| 15 | Saturday | June 5 | 7:05pm | at Fairbanks Grizzlies | L 36-64 | 2-10 | Carlson Center | |
| 16 | Saturday | June 12 | 7:05pm | at Chicago Slaughter | W 27-20 | 3-10 | Sears Centre | |
| 17 | Saturday | June 19 | 7:05pm | Bloomington Extreme | L 21-35 | 3-11 | La Crosse Center | |