The 2010 Kazan Kremlin Cup was a professional tennis tournament played on indoor hard courts. It was part of the 2010 ATP Challenger Tour. It took place in Kazan, Russia, between 1 and 7 February 2010.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Julian Reister | 172 | 1 | ||
| Michał Przysiężny | 192 | 2 | ||
 Kazakhstan | Yuri Schukin | 205 | 3 | |
 Russian Federation | Alexander Kudryavtsev | 206 | 4 | |
 Ukraine | Ivan Sergeyev | 209 | 5 | |
 Spain | Adrián Menéndez Maceiras | 222 | 6 | |
| Russian Federation | Konstantin Kravchuk | 244 | 7 | |
 Slovakia | Pavol Červenák | 252 | 8 |
The following players received wildcards into the singles main draw:
Marat Gilmanov Vladislav Gorshenin Anton Manegin Daniyal ZagidullinThe following players received entry from the qualifying draw:
Evgeny Donskoy Mikhail Ledovskikh Alexander Lobkov Denis MatsukevichSee main article: 2010 Kazan Kremlin Cup – Singles. 
Michał Przysiężny def. Julian Reister, 7 - 6(5), 6 - 4
See main article: 2010 Kazan Kremlin Cup – Doubles. 
Jan Mertl / Yuri Schukin def. Tobias Kamke / Julian Reister, 6 - 2, 6 - 4.