| Champ: |  Blaž Kavčič |
| Runner: |  Michael Venus |
| Score: | 7–6(6), 7–6(5) |
| Type: | singles doubles |
See main article: 2010 Karshi Challenger. Rainer Eitzinger was the champion in 2009, but he decided to not compete this year.
Blaž Kavčič won the final against Michael Venus 7–6(6), 7–6(5).