The 2010 Ixian Grand Aegean Tennis Cup was a professional tennis tournament played on outdoor hard courts. It was part of the Tretorn SERIE+ of the 2010 ATP Challenger Tour. It took place in Rhodes, Greece between April 26 and May 2, 2010.
See main article: 2010 Aegean Tennis Cup – Singles. 
Dudi Sela def. Rainer Schüttler, 7–6(3), 6–3
See main article: 2010 Aegean Tennis Cup – Doubles. 
Dustin Brown / Simon Stadler def. 
Jonathan Marray / Jamie Murray, 7-6(4), 6-7(4), [10-7]
| Nationality | Player | Ranking* | Seeding | |
|---|---|---|---|---|
| Marco Chiudinelli | 56 | 1 | ||
| Israel | Dudi Sela | 70 | 2 | |
| Rainer Schüttler | 99 | 3 | ||
| Lu Yen-hsun | 102 | 4 | ||
| Jamaica | Dustin Brown | 105 | 5 | |
| Israel | Harel Levy | 124 | 6 | |
| Stéphane Bohli | 132 | 7 | ||
| Björn Phau | 142 | 8 |
The following players received entry from the qualifying draw:
