The 2010 Intersport Heilbronn Open (known as the 2010 Intersport Heilbronn Open presented by Wilson for sponsorship reasons) was a professional tennis tournament played on indoor hard courts. It was part of the 2010 ATP Challenger Tour. It took place in Talheim, Germany between 25 and 31 January 2010.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Michael Berrer | 66 | 1 | ||
| Daniel Brands | 91 | 2 | ||
 Czech Republic | Jan Hernych | 109 | 3 | |
| Mario Ančić | 115 | 4 | ||
 Israel | Harel Levy | 116 | 5 | |
 Slovakia | Karol Beck | 117 | 6 | |
| Björn Phau | 118 | 7 | ||
 Ukraine | Oleksandr Dolgopolov Jr. | 123 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following player received the lucky loser spot:
See main article: 2010 Intersport Heilbronn Open – Singles. Michael Berrer def. 
Andrey Golubev, 6–3, 7–6(7–4).
See main article: 2010 Intersport Heilbronn Open – Doubles. 
Sanchai Ratiwatana / Sonchat Ratiwatana def. Mario Ančić / Lovro Zovko, 6–4, 7–5.
