| Year: | 2010 |
| Team: | Illinois State Redbirds |
| Sport: | football |
| Conference: | Missouri Valley Football Conference |
| Short Conf: | MVFC |
| Record: | 6–5 |
| Conf Record: | 4–4 |
| Head Coach: | Brock Spack |
| Hc Year: | 2nd |
| Off Coach: | Luke Huard |
| Oc Year: | 1st |
| Def Coach: | Phil Elmassian |
| Dc Year: | 2nd |
| Mvp: | Marvon Sanders, Eric Brunner |
| Captain: | Dane Zumbahlen, Kelvyn Hemphill |
| Stadium: | Hancock Stadium |
The 2010 Illinois State Redbirds football team represented Illinois State University as a member of the Missouri Valley Football Conference (MVFC) during the 2010 NCAA Division I FCS football season. Led by second-year head coach Brock Spack, the Redbirds compiled an overall record of 6–5 with a mark of 4–4 in conference play, placing in a six-way tie for third in the MVFC. Illinois State played home games at Hancock Stadium in Normal, Illinois.