The 2010 Grand Prix Hassan II was a men's tennis tournament played on outdoor clay courts. It was the 26th edition of the Grand Prix Hassan II, and an ATP Tour World 250 event on the 2010 ATP World Tour. It was the 26th edition of the tournament and took place at the Complexe Al Amal in Casablanca, Morocco, from 5 April through 11 April 2010. `First-seeded Stan Wawrinka won the singles title.
| Athlete | Nationality | Ranking* | Seeding | |
|---|---|---|---|---|
| Stan Wawrinka | Switzerland | 23 | 1 | |
| Guillermo García-López |  Spain | 41 | 2 | |
| Victor Hănescu |  Romania | 42 | 3 | |
| Łukasz Kubot |  Poland | 43 | 4 | |
| Paul-Henri Mathieu |  France | 44 | 5 | |
| Simon Greul | Germany | 55 | 6 | |
| Olivier Rochus |  Belgium | 59 | 7 | |
| Florent Serra | France | 61 | 8 |
The following players received wildcards into the main draw:
The following players received entry via qualifying:
See main article: 2010 Grand Prix Hassan II – Singles. Stan Wawrinka defeated Victor Hănescu, 6–2, 6–3
See main article: 2010 Grand Prix Hassan II – Doubles. 
Robert Lindstedt / Horia Tecău defeated 
Rohan Bopanna / 
Aisam-ul-Haq Qureshi, 6–2, 3–6, [10–7]
