| Year: | 2010 |
| Team: | Grambling State Tigers |
| Sport: | football |
| Conference: | Southwestern Athletic Conference |
| Short Conf: | SWAC |
| Division: | West Division |
| Tsnrank: | 23 |
| Record: | 9–2 |
| Conf Record: | 8–1 |
| Head Coach: | Rod Broadway |
| Hc Year: | 4th |
| Stadium: | Eddie G. Robinson Memorial Stadium |
| Champion: | SWAC West Division co-champion |
The 2010 Grambling State Tigers football team represented Grambling State University as a member of the Southwestern Athletic Conference (SWAC) during the 2010 NCAA Division I FCS football season. Led by fourth-year head coach Rod Broadway, the Tigers compiled an overall record of 9–2 and a mark of 8–1 in conference play, and finished as co-champion in the SWAC West Division.