| Year: | 2010 |
| Team: | Gardner–Webb Runnin' Bulldogs |
| Sport: | football |
| Conference: | Big South Conference |
| Short Conf: | Big South |
| Record: | 4–7 |
| Conf Record: | 2–4 |
| Head Coach: | Steve Patton |
| Hc Year: | 14th |
| Def Coach: | John Windham |
| Dc Year: | 4th |
The 2010 Gardner–Webb Runnin' Bulldogs football team represented Gardner–Webb University as a member of the Big South Conference during the 2010 NCAA Division I FCS football season. Led by Steve Patton in his 14th-year and final season as head coach, the Runnin' Bulldogs compiled an overall record of 4–7 with a mark of 2–4 in conference play, tying for fourth place in the Big South. Gardner–Webb played home games at Ernest W. Spangler Stadium in Boiling Springs, North Carolina.