| Main Name: | Portugal OpenEstoril Open |
| Champ: |  Albert Montañés |
| Runner: | Frederico Gil |
| Score: | 6–2, 6–7(5–7), 7–5 |
| Before Name: | Estoril Open |
| After Name: | Estoril Open |
See main article: 2010 Estoril Open. Albert Montañés defend his 2009 title, after winning against Frederico Gil in the final. The Spaniard became the second player to win back-to-back titles at this tournament, following Thomas Muster in 1995 and 1996.
The top four seeds receive a bye into the second round.