| Competition: | Esiliiga |
| Season: | 2010 |
| Biggest Home Win: | TJK Legion 8–0 Rakvere |
| Biggest Away Win: | Rakvere 1–6 Flora U21 |
| Highest Scoring: | TJK Legion 8–0 Rakvere Flora U21 6–2 Rakvere |
| Matches: | 60 |
| Total Goals: | 189 |
| Prevseason: | 2009 |
| Nextseason: | 2011 |
The 2010 season of the Esiliiga, the second level in the Estonian football system, is the 20th season in the league's history. It starts in March and ends in November. The defending champions are Levadia II, who are unable for promotion as they are the reserve team for Meistriliiga side Levadia.
| Club | Location | Stadium | Current manager | |
|---|---|---|---|---|
| Flora II | Tallinn | Sportland Arena |  Zaur Tšilingarašvili | |
| Flora Rakvere | Rakvere | Rakvere linnastaadion | Urmas Kirs | |
| Ajax | Tallinn | FC Ajax Stadium | Aleksandr Puštov | |
| Levadia II | Tallinn | Maarjamäe kunstmuru | Urmas Hepner | |
| Tallinna Kalev | Tallinn | Kalev Keskstaadion artificial turf | Sergei Ratnikov | |
| Orbiit | Jõhvi | Jõhvi linnastaadion | Valeri Kulatšenko | |
| Kiviõli Tamme Auto | Kiviõli | Kiviõli Stadium | Erik Šteinberg | |
| TJK Legion | Tallinn | Wismar Stadium | Viktor Passikuta | |
| Warrior | Valga | Sportland Arena | Zaur Tšilingarašvili | |
| Vaprus | Pärnu | Pärnu Kalev Stadium | Ants Kommussaar |
Each team plays every opponent four times, twice at home and twice on the road, for a total of 36 games.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 | Tõnis Starkopf | Kiviõli Tamme Auto | 28 |
| 2 | Sergei Tasso | Lasnamäe Ajax | 24 |
| 3 | Artur Rättel | Levadia II | 18 |
| 4 | Jaan Leimann | Flora II | 15 |
| 5 | Dmitri Kirilov | Kiviõli Tamme Auto | 14 |
| Maksim Kisseljov | TJK Legion | ||
| 7 | Hannes Anier | Flora II | 13 |
| Taavi Laurits | Vaprus | ||
| Marten Mütt | Flora II | ||
| 10 | Sergei Akimov | Rakvere Flora | 12 |
 Yaroslav Dmitriev | Levadia II | ||
| Raiko Karpov | Warrior | ||
| Ilja Monakov | Tallinna Kalev |
| Month | Manager of the Month | Player of the Month | |||
|---|---|---|---|---|---|
| Manager | Club | Player | Club | ||
| March | Sergei Ratnikov | Tallinna Kalev | Sergei Tasso | Ajax | |
| April | Andrei Borissov | Ajax | Artjom Dmitrijev | Levadia II | |
| May | Aleksandr Pushtov | Levadia II | Andrei Borissov | Ajax | |
| June | Aleksandr Pushtov | Levadia II | Andrei Veis | Flora II | |
| July | Zaur Tšilingarašvili | Flora II | Tõnis Starkopf | Kiviõli Tamme Auto | |
| August | Vitali Bolšakov | Orbiit | Aleksandr Marašov | Orbiit | |