The 2010 Swiss Indoors was a men's tennis tournament played on indoor hard courts. It was the 41st edition of the event known that year as the Davidoff Swiss Indoors, and was part of the 500 Series of the 2010 ATP World Tour. It was held at the St. Jakobshalle in Basel, Switzerland, from 1 November through 7 November 2010. Roger Federer won the singles title.
See main article: 2010 Swiss Indoors – Singles. Roger Federer defeated 
Novak Djokovic, 6–4, 3–6, 6–1
See main article: 2010 Swiss Indoors – Doubles. 
Bob Bryan / Mike Bryan defeated 
Daniel Nestor / Nenad Zimonjić, 6–3, 3–6, [10–3]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Roger Federer | 2 | 1 | ||
| Novak Djokovic | 3 | 2 | ||
| Tomáš Berdych | 6 | 3 | ||
| Andy Roddick | 9 | 4 | ||
| Jürgen Melzer | 12 | 5 | ||
| Marin Čilić | 14 | 6 | ||
| Ivan Ljubičić | 17 | 7 | ||
| John Isner | 19 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entries as a Lucky losers into the singles main draw:
