| Club: | Cruzeiro |
| Season: | 2010 |
| Manager: |  Adilson Batista(until 3 June 2010) Cuca |
| Mgrtitle: | Manager |
| Chairman: | Zezé Perrella |
| Chrtitle: | Chairman |
| League: | Série A |
| League Result: | 2nd |
| Cup1: | Campeonato Mineiro |
| Cup1 Result: | Semi-finals |
| Cup2: | Copa Libertadores |
| Cup2 Result: | Quarter-finals |
| League Topscorer: | Walter Montillo and Wellington Paulista (7) |
| Season Topscorer: | Thiago Ribeiro (21) |
| Highest Attendance: | 48,602 (v São Paulo in the Copa Libertadores) |
| Lowest Attendance: | 2,415 (v Uberaba in the Campeonato Mineiro) |
| Prevseason: | 2009 |
| Nextseason: | 2011 |
The 2010 season is Cruzeiro's eighty-ninth season in existence and the club's fortieth consecutive season in the top flight of Brazilian football.
Professional players able to play in the junior team
Junior players with first team experience
Out on loan:
| Position | Name | Nationality |
|---|---|---|
| Coach | Cuca | Brazil |
| Assistant coach | Celso Roth | Brazil |
| Coach Suffes | Humberto Ferreira | Brazil |
| Goalkeeping coach | Robertinho | Brazil |
| Fitness coaches | Flavio de Oliveira | Brazil |
| Quintiliano Lemos | Brazil | |
| Eduardo Freitas | Brazil | |
| Physiologists | Eduardo Pimenta | Brazil |
| Rodrigo Morandi | Brazil | |
| Physiotherapists | André Rocha | Brazil |
| Charles Costa | Brazil | |
| Ronner Bolognani | Brazil | |
| João Salomão | Brazil | |
| Doctors | Sérgio Freire Júnior | Brazil |
| Walace Espada | Brazil | |
| Leonardo Corradi | Brazil | |
| Masseurs | Barjão | Brazil |
| Edmar Antônio Silva | Brazil | |
| Hélio Gomes | Brazil | |
See main article: article and 2010 Campeonato Mineiro.
See main article: article and 2010 Campeonato Brasileiro Série A.
See main article: article and 2010 Copa Libertadores.
Group 7
| width=60 | Position | width=60 | Nation | width=60 | Playing position | width=150 | Name | width=80 | Campeonato Mineiro | width=80 | Copa Libertadores | width=80 | Campeonato Brasileiro | width=80 | Others | width=80 | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | FW | Thiago Ribeiro | 5 | 8 | 8 | 2 | 23 | |||||||||
| 2 | | FW | Wellington Paulista | 4 | 1 | 7 | 4 | 16 | |||||||||
| 3 | | FW | Kléber | 5 | 7 | 2 | 0 | 14 | |||||||||
| 4 |  | MF | Walter Montillo | 0 | 0 | 7 | 0 | 7 | |||||||||
| 5 | | MF | Roger | 2 | 0 | 4 | 0 | 6 | |||||||||
| 6 | | MF | Gilberto | 2 | 1 | 2 | 0 | 5 | |||||||||
| 7 | | MF | Fabinho | 2 | 1 | 1 | 0 | 4 | |||||||||
| = | | MF | Henrique | 0 | 0 | 4 | 0 | 4 | |||||||||
| 8 | | MF | Bernardo | 2 | 1 | 0 | 0 | 3 | |||||||||
| = | | FW | Ernesto Farías | 0 | 0 | 3 | 0 | 3 | |||||||||
| = | | DF | Leonardo Silva | 3 | 0 | 0 | 0 | 3 | |||||||||
| = | | MF | Pedro Ken | 1 | 2 | 0 | 0 | 3 | |||||||||
| = | | DF | Cláudio Caçapa | 1 | 0 | 1 | 1 | 3 | |||||||||
| = | | FW | Robert | 0 | 0 | 3 | 0 | 3 | |||||||||
| = | | FW | Wallyson | 0 | 0 | 3 | 0 | 3 | |||||||||
| 9 | | FW | Anderson Lessa | 2 | 0 | 0 | 0 | 2 | |||||||||
| = | | DF | Diego Renan | 1 | 1 | 0 | 0 | 2 | |||||||||
| = | | FW | Eliandro | 1 | 1 | 0 | 0 | 2 | |||||||||
| = | | DF | Gil | 1 | 0 | 1 | 0 | 2 | |||||||||
| = |  | FW | Joffre Guerrón | 0 | 1 | 1 | 0 | 2 | |||||||||
| = | | DF | Jonathan | 1 | 1 | 0 | 0 | 2 | |||||||||
| = | | FW | Kieza | 2 | 0 | 0 | 0 | 2 | |||||||||
| 10 | | DF | Edcarlos | 0 | 0 | 1 | 0 | 1 | |||||||||
| 9 | | MF | Everton | 0 | 0 | 1 | 0 | 1 | |||||||||
| = | | DF | Léo | 0 | 0 | 1 | 0 | 1 | |||||||||
| = | | MF | Marquinhos Paraná | 0 | 1 | 0 | 0 | 1 | |||||||||
| = | | DF | Rômulo | 0 | 0 | 1 | 0 | 1 | |||||||||
| / | / | / | Own goals | 0 | 0 | 2 | 0 | 2 | |||||||||
| Total | 35 | 26 | 53 | 7 | 121 |