The 2010 Copa Telmex was a men's tennis tournament played on outdoor clay courts. It was the 13th edition of the Copa Telmex, and was part of the ATP World Tour 250 series of the 2010 ATP World Tour. It took place in Buenos Aires, Argentina, from February 15 through February 21, 2010. Juan Carlos Ferrero won the singles title.
The singles line up was led by 2007 Copa Telmex champion and 2009 Copa Telmex runner-up Juan Mónaco, David Ferrer, Nicolás Almagro and Juan Carlos Ferrero. other players were 2008 champion David Nalbandian, Richard Gasquet, Igor Andreev, Albert Montañés.
See main article: 2010 Copa Telmex – Singles. 
Juan Carlos Ferrero defeated David Ferrer 5–7, 6–4, 6–3
See main article: 2010 Copa Telmex – Doubles. 
Sebastián Prieto / Horacio Zeballos defeated Simon Greul / 
Peter Luczak, 7–6(7–4), 6–3
| Athlete | Nationality | Ranking* | Seeding | |
|---|---|---|---|---|
| David Ferrer | Spain | 17 | 1 | |
| Juan Carlos Ferrero | Spain | 22 | 2 | |
| Nicolás Almagro | Spain | 26 | 3 | |
| Juan Mónaco | Argentina | 27 | 4 | |
| Albert Montañés | Spain | 30 | 5 | |
| Igor Andreev |  Russia | 41 | 6 | |
| Victor Hănescu |  Romania | 44 | 7 | |
| Horacio Zeballos | Argentina | 49 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
The following players received Special Exempts into the main draw:
