The 2010 Copa Sony Ericsson Colsanitas was a women's tennis tournament played on outdoor clay courts. It was the 13th edition of the Copa Sony Ericsson Colsanitas, and was on the International category of the 2010 WTA Tour. It took place at the Club Campestre El Rancho in Bogotá, Colombia, from 15 February through 21 February 2010. Unseeded Mariana Duque Mariño won the singles title.
Last year's finalist Gisela Dulko was the top-seeded player. Also in the field were 2008 semifinalist Carla Suárez Navarro, Italian Sara Errani, last year's semifinalist Patricia Mayr, Klára Zakopalová, Angelique Kerber, and Arantxa Parra Santonja.
| Country | Player | Ranking1 | Seeding | |
|---|---|---|---|---|
 Argentina | Gisela Dulko | 35 | 1 | |
 Spain | Carla Suárez Navarro | 42 | 2 | |
 Italy | Sara Errani | 45 | 3 | |
| Polona Hercog | 63 | 4 | ||
| Angelique Kerber | 85 | 5 | ||
 Czech Republic | Sandra Záhlavová | 86 | 6 | |
| Czech Republic | Klára Zakopalová | 90 | 7 | |
| Spain | Arantxa Parra Santonja | 93 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
 Ukraine | Mariya Koryttseva |  Canada | Marie-Ève Pelletier | 124 | 1 | |
| Gisela Dulko | Edina Gallovits | 128 | 2 | |||
| Spain | Lourdes Domínguez Lino | Arantxa Parra Santonja | 186 | 3 | ||
| Canada | Sharon Fichman | Mashona Washington | 198 | 4 |
The following pairs received wildcards into the doubles main draw:
Bianca Botto / 
Mariana Duque Mariño
Martina Frantová / Karen Ramírez RiveraSee main article: 2010 Copa BBVA-Colsanitas – Singles. Mariana Duque Mariño defeated Angelique Kerber 6–4, 6–3
See main article: 2010 Copa BBVA-Colsanitas – Doubles. Gisela Dulko / 
Edina Gallovits defeated Olga Savchuk / 
Anastasiya Yakimova 6–2, 7–6(8–6)
