| Champ: | Robin Haase |
| Runner: |  Ivo Minář |
| Score: | 6–4, 6–3 |
| Type: | singles doubles |
See main article: 2010 Città di Como Challenger. Alexandr Dolgopolov was the defending champion, but chose not to compete this year.
Robin Haase won the final against Ivo Minář 6–4, 6–3.