The 2010 Aircel Chennai Open was a tennis tournament played on outdoor hard courts. It is the 15th edition of the Chennai Open, and part of the 250 series of the 2010 ATP World Tour. It takes place at the SDAT Tennis Stadium in Chennai, India, from 4 January through 10 January 2010. Second-seeded Marin Čilić won the singles title.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Sweden | Robin Söderling | 8 | 1 | |
| Marin Čilić | 14 | 2 | ||
| Stanislas Wawrinka | 21 | 3 | ||
 Serbia | Janko Tipsarević | 38 | 4 | |
 Israel | Dudi Sela | 43 | 5 | |
| Simon Greul | 59 | 6 | ||
| Michael Berrer | 74 | 7 | ||
 United States | Rajeev Ram | 79 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2010 Aircel Chennai Open – Singles. Marin Čilić defeated Stanislas Wawrinka, 7 - 6(7–2), 7 - 6(7–3).
See main article: 2010 Aircel Chennai Open – Doubles. 
Marcel Granollers / Santiago Ventura defeated Lu Yen-hsun / Janko Tipsarević, 7 - 5, 6 - 2.
