See main article: 2010 Challenger of Dallas.
Prakash Amritraj and Rajeev Ram were the defending champions, but they chose not to participate this year.
Scott Lipsky and David Martin won in the final 7–6(9–7), 6–3 against Vasek Pospisil and Adil Shamasdin.
Scott Lipsky / David Martin (champions)
Harsh Mankad (quarterfinals) Lester Cook / Travis Rettenmaier (first round) Bobby Reynolds / Ryan Sweeting (first round)