The 2010 Challenger DCNS de Cherbourg was a professional tennis tournament played on indoor hard courts. It was part of the 2010 ATP Challenger Tour. It took place in Cherbourg-Octeville, France between 1 and 7 March 2010.
| Nationality | Player | Ranking* | Seeding | |
|---|---|---|---|---|
 France | Arnaud Clément | 67 | 1 | |
| France | Josselin Ouanna | 118 | 2 | |
| Kevin Kim | 123 | 3 | ||
 Belgium | Kristof Vliegen | 127 | 4 | |
| France | David Guez | 136 | 5 | |
 Czech Republic | Jan Hernych | 140 | 6 | |
| France | Laurent Recouderc | 141 | 7 | |
| Stéphane Bohli | 142 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2010 Challenger DCNS de Cherbourg – Singles. Nicolas Mahut def. 
Gilles Müller, 6–4, 6–3
See main article: 2010 Challenger DCNS de Cherbourg – Doubles. Nicolas Mahut / Édouard Roger-Vasselin def. 
Harsh Mankad / 
Adil Shamasdin, 6–2, 6–4
