| Competition: | Torneo Postobón |
| Season: | 2010 |
| Winners: | Itagüí Ditaires |
| Promoted: | Itagüí Ditaires |
| League Topscorer: | Alvaro Barrios (21 goals) |
| Biggest Home Win: | Real Santander 7-0 Valledupar |
| Biggest Away Win: | Academia 1-5 Itagüí Ditaires Juventud Girardot 0-4 Valledupar |
| Highest Scoring: | Real Santander 7-0 Valledupar Itagüí Ditaires 6-1 Juventud Girardot Alianza Petrolera 6-1 Dépor |
| Prevseason: | 2009 |
| Nextseason: | 2011 |
The 2010 Categoría Primera B season is the 21st season since its founding and is officially called the 2010 Torneo Postobón for sponsorship reasons.
| Round 9 (Derbies) - April 10 and 11, 2010 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Date | Time | Venue | Home | Score | Away | ||||||
| Sat. | 14:30 | Compensar | Academia | 3 - 1 | Bogotá F. C. | ||||||
| 15:30 | Alfonso López | Bucaramanga | 2 - 1 | Juventud | |||||||
| Metropolitano Roberto Meléndez | Barranquilla F. C. | 0 - 0 | Atlético de la Sabana | ||||||||
| Armando Maestre Pavajeau | Valledupar | 0 - 1 | Unión Magdalena | ||||||||
| Metropolitano Ciudad de Itagüí | Itagüi | 0 - 1 | Rionegro | ||||||||
| Manuel Calle Lombana | Centauros | 1 - 0 | Patriotas | ||||||||
| Sun. | 15:30 | Daniel Villa Zapata | Alianza Petrolera | 2 - 2 | Real Santander | ||||||
| Departamental Libertad | Deportivo Pasto | 1 - 2 | Depor F. C. | ||||||||
| Polideportivo El Cristal | Pacífico F. C. | 1 - 1 | Expreso Rojo | ||||||||
| Round 27 (Derbies) - September 8, 2010 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Date | Time | Venue | Home | Score | Away | ||||||
| Wed. | 15:30 | Alfonso López | Real Santander | 3 - 2 | Alianza Petrolera | ||||||
| Municipal Los Zipas | Expreso Rojo | 1 - 2 | Pacífico F. C. | ||||||||
| Cacique Jamundí | Depor F. C. | 0 - 0 | Deportivo Pasto | ||||||||
| Alfonso López Pumarejo | Bogotá F. C. | 4 - 0 | Academia | ||||||||
| 16:30 | Luis Antonio Duque | Juventud | 1 - 3 | Bucaramanga | |||||||
| 19:30 | Arturo Cumplido Sierra | Atlético de la Sabana | 1 - 0 | Barranquilla F. C. | |||||||
| Eduardo Santos | Union Magdalena | 0 - 1 | Valledupar | ||||||||
| Alberto Grisales | Rionegro | 3 - 4 | Itagüi | ||||||||
| De La Independencia | Patriotas | 5 - 0 | Centauros | ||||||||