| Date: | July 5–11 |
| Edition: | 35th |
| Category: | ATP World Tour 250 |
| Draw: | 32S / 16D |
| Prize Money: | $442,500 |
| Surface: | Grass / outdoors |
| Location: | Newport, Rhode Island, United States |
| Venue: | International Tennis Hall of Fame |
| Champs: |  Mardy Fish |
| Champd: |  Carsten Ball / Chris Guccione |
| Main Name: | Hall of Fame Tennis Championships |
The 2010 Hall of Fame Tennis Championships (also known as the Campbell's Hall of Fame Tennis Championships for sponsorship reasons) was a men's tennis tournament played on outdoor grass courts. It was the 35th edition of the Hall of Fame Tennis Championships, and was part of the ATP World Tour 250 series of the 2010 ATP World Tour. It took place at the International Tennis Hall of Fame in Newport, Rhode Island, United States, from July 5 through July 11, 2010. Fifth-seeded Mardy Fish won the singles title.
| Player | Nationality | Ranking* | Seeding |
|---|---|---|---|
| Sam Querrey | United States | 21 | 1 |
| Santiago Giraldo |  Colombia | 54 | 2 |
| Alejandro Falla | Colombia | 60 | 3 |
| Olivier Rochus |  Belgium | 68 | 4 |
| Mardy Fish | United States | 73 | 5 |
| Karol Beck |  Slovakia | 88 | 6 |
| Rajeev Ram | United States | 93 | 7 |
| Taylor Dent | United States | 97 | 8 |
The following players received wildcards into the singles main draw
The following players received entry from the qualifying draw:
See main article: 2010 Hall of Fame Tennis Championships – Singles. Mardy Fish defeated Olivier Rochus 5–7, 6–3, 6–4
See main article: 2010 Hall of Fame Tennis Championships – Doubles. Carsten Ball / Chris Guccione defeated 
Santiago González / Travis Rettenmaier 6–3, 6–4
