The 2010 Busan Open Challenger Tennis was a professional tennis tournament played on outdoor hard courts. It was part of the 2010 ATP Challenger Tour. It took place in Busan, South Korea between May 10 and May 16, 2010.
| Nationality | Player | Ranking* | Seeding | |
|---|---|---|---|---|
| Rainer Schüttler | 75 | 1 | ||
| Lu Yen-hsun | 78 | 2 | ||
 Japan | Go Soeda | 155 | 3 | |
 Austria | Alexander Peya | 225 | 4 | |
| Brendan Evans | 236 | 5 | ||
| Simon Stadler | 269 | 7 | ||
| Japan | Tatsuma Ito | 272 | 8 |
The following players received wildcards into the singles main draw:
Lim Yong-Kyu Jun Woong-Sun Nam Ji Sung Jeong Suk-YoungThe following players received entry from the qualifying draw:
An Jae-Sung Hiroki Kondo (as a Lucky loser) Toshihide MatsuiSee main article: 2010 Busan Open Challenger Tennis – Singles. Lim Yong-Kyu def. Lu Yen-hsun, 6–1, 6–4
See main article: 2010 Busan Open Challenger Tennis – Doubles. Alexander Peya / 
Rameez Junaid def. 
Pierre-Ludovic Duclos / Yang Tsung-hua, 6–4, 7–5