| Date: | August 2 – August 8 |
| Edition: | 66th |
| Location: | Kitzbühel, Austria |
| Champs: |  Andreas Seppi |
| Champd: |  Dustin Brown / Rogier Wassen |
The 2010 Austrian Open Kitzbühel was a professional tennis tournament played on outdoor red clay courts. It was the eighth edition of the tournament which is part of the 2010 ATP Challenger Tour. It took place in Kitzbühel, Austria between 2 and 8 August 2010.
Guillermo García-López won in the singles competition and André Sá and Marcelo Melo in the doubles competition in 2009, when the tournament was part of the ATP World Tour 250 series.
| Nationality | Player | Ranking* | Seeding | |
|---|---|---|---|---|
| Italy | Andreas Seppi | 55 | 1 | |
 Czech Republic | Jan Hájek | 78 | 2 | |
| Pablo Cuevas | 85 | 3 | ||
 Australia | Peter Luczak | 93 | 4 | |
| Björn Phau | 97 | 5 | ||
| Jamaica | Dustin Brown | 98 | 6 | |
 Spain | Pablo Andújar | 100 | 7 | |
| Italy | Paolo Lorenzi | 106 | 8 |
The following players received wildcards into the singles main draw:
The following players received a Special Exempt into the main draw:
The following players received entry from the qualifying draw:
Andreas Haider-Maurer Gerald Kamitz Jan Minář
Grzegorz PanfilSee main article: 2010 Austrian Open Kitzbühel – Singles. Andreas Seppi def. 
Victor Crivoi, 6–2, 6–1
See main article: 2010 Austrian Open Kitzbühel – Doubles. Dustin Brown / Rogier Wassen def. Hans Podlipnik-Castillo / Max Raditschnigg, 3–6, 7–5, [10–7]
