| Mode: | football |
| Year: | 2010 |
| Team: | Appalachian State Mountaineers |
| Conference: | Southern Conference |
| Short Conf: | Southern |
| Tsnrank: | 4 |
| Fcscoachrank: | 4 |
| Record: | 10–3 |
| Conf Record: | 7–1 |
| Head Coach: | Jerry Moore |
| Hc Year: | 22nd |
| Off Coach: | Collaborative[1] |
| Def Coach: | Dale Jones |
| Dc Year: | 1st |
| Off Scheme: | Multiple spread |
| Def Scheme: | 3–4 |
| Stadium: | Kidd Brewer Stadium |
| Champion: | SoCon co-champion |
| Bowl: | FCS Quarterfinals |
| Bowl Result: | L 24–42 vs. Villanova |
The 2010 Appalachian State Mountaineers football team represented Appalachian State University in the 2010 NCAA Division I FCS football season. The team was led by head coach Jerry Moore in his 22nd season and played their home games at Kidd Brewer Stadium. They were members of the Southern Conference.
See also: 2010 Florida Gators football team.