See main article: 2010 ASB Classic.
Elena Dementieva was the defending champion, but chose not to participate this year.
In the final, Yanina Wickmayer defeated Flavia Pennetta, 6–3, 6–2.
Flavia Pennetta (final)
Li Na (first round)
Yanina Wickmayer (champion) Francesca Schiavone (semifinals)
Virginie Razzano (second round)
Elena Vesnina (second round) Aravane Rezaï (second round)
Anabel Medina Garrigues (first round)