The 2010 İstanbul Cup was a women's tennis tournament played on outdoor hard courts. It was the 6th edition of the İstanbul Cup, and was part of the WTA International tournaments of the 2010 WTA Tour. It took place in Istanbul, Turkey, from 26 July through 1 August 2010. Anastasia Pavlyuchenkova won the singles title.
| Player | Nationality | Ranking* | Seed | |
|---|---|---|---|---|
 Italy | 8 | 1 | ||
| Petra Kvitová |  Czech Republic | 30 | 2 | |
 Russia | 31 | 3 | ||
 Kazakhstan | 32 | 4 | ||
| Bulgaria | 34 | 5 | ||
 | 36 | 6 | ||
| Czech Republic | 46 | 7 | ||
| Patty Schnyder | Switzerland | 51 | 8 |
The following players received wildcards into the singles main draw
The following players received entry from the qualifying draw:[1]
See main article: 2010 İstanbul Cup – Singles. Anastasia Pavlyuchenkova defeated Elena Vesnina, 5–7, 7–5, 6–4
See main article: 2010 İstanbul Cup – Doubles. Eleni Daniilidou / Jasmin Wöhr defeated Maria Kondratieva / Vladimíra Uhlířová, 6–4, 1–6, [11–9]
