| Competition: | Nigeria Premier League |
| Season: | 2010–11 |
| Winners: | Dolphins |
| Relegated: | Plateau United, Zamfara United, Crown F.C., JUTH F.C. |
| Continentalcup1: | 2012 CAF Champions League |
| Continentalcup1 Qualifiers: | Dolphins Sunshine Stars |
| Continentalcup2: | 2012 CAF Confederation Cup |
| Continentalcup2 Qualifiers: | Warri Wolves Heartland (cup winner) |
| Matches: | 380 |
| Total Goals: | 786 |
| League Topscorer: | Jude Aneke - Kaduna United (20) |
| Biggest Home Win: | Plateau United 7-0 vs Kwara United (23 Oct. 2011) |
| Biggest Away Win: | Kwara United 2-0 at JUTH (11 Dec. 2010) Sharks F.C. 3-1 at Crown F.C. (2 November 2011) |
| Highest Scoring: | Enugu Rangers 5, Ocean Boys 2 (21 Nov. 2010) Sharks 4, Crown 3 (26 Feb. 2011) Plateau United 7-0 vs Kwara United (23 Oct. 2011) |
| Longest Wins: | Dolphins - 5 games from 22 Dec. 2010 to 22 Jan. 2011 |
| Longest Unbeaten: | 8 games: Bukola Babes (6 wins, 2 ties) from 22 Dec. to 16 Feb. |
| Longest Winless: | 9 games: Plateau United (3 ties, 6 losses) from 23 Dec. to 20 Feb. |
| Longest Losses: | Crown - 5 games from 22 Dec. to 23 Jan. |
| Highest Attendance: | 26,000: Enyimba at K. Pillars 11 Dec. 2010 |
| Prevseason: | 2009–10 |
| Nextseason: | 2012 |
The 2010–11 Nigeria Premier League was the 40th season of the competition since its inception, and the 21st since the rebranding of the league as the "Professional League". Enyimba International were the defending champions.
The season was originally supposed to start 25 September, then was delayed to 2 October. However after a series of meetings and threatened lawsuits, the league announced that it would play with 24 teams, including the four teams relegated from the previous season. The tentative compromise plans included two divisions of 12 teams each with the top two making the season-ending Super Four, mirroring the league's format in the 2006 and 2007 seasons. This idea was canceled by the NPL on October 7 and the league returned to 20 teams for the season.
The season was delayed again to start the weekend of 23 October,[1] and delayed yet again to 6 November because of issues with the assignment of referees.Due to enforcement of minimum pitch standards, several teams have been made to play in different stadiums outside their home cities.
The second half of the season began 11 May after a six-week break, including two delays for national elections. The season was finished on 13 November 2011 after another six-week delay to allow for the Federation Cup and teams playing on the continent to concentrate on their fixtures.
| Team | Manager | Captain | Kit Makers | Sponsor | |
|---|---|---|---|---|---|
| Bukola Babes |  Kabiru Sulaiman | Abubakar Yusuf | |||
| Crown FC | Oladunni Oyekale | Johnson Abiodun | |||
| Dolphins | Stanley Eguma | Emmanuel Godwin | |||
| Enugu Rangers | Alphonsus Dike | Austin Iyangbe | |||
| Enyimba | Okey Emordi | Okechukwu Odita | Joma | ||
| Gombe United | Bernard Ogbe | ||||
| Heartland |  Lodewijk de Kruif | Chinedu Efugh | |||
| JUTH F.C. |  Emmanuel Deutsch | ||||
| Kaduna United |  Maurice Cooreman | Papa Idris | |||
| Kano Pillars | Ladan Bosso | ||||
| Kwara United | Kadiri Ikhana | ||||
| Lobi Stars | John Zaki | ||||
| Niger Tornadoes | Justin Tenger | Kelvin Njoku | |||
| Ocean Boys | Samson Unuanel | ||||
| Plateau United | Nduka Ndubuisi | Ajibade Omolade | |||
| Sharks | John Obuh | Odinga Odinga | |||
| Shooting Stars | Fatai Amoo | Shakiru Lawal | OWU Sportswear | ||
| Sunshine Stars | Gbenga Ogunbote | James Moses | |||
| Warri Wolves | Paul Aigbogun | Goodluck Nnamadu | Lotto | Oceanic Bank | |
| Zamfara United | Bello Garba Gusau |
| Team | Outgoing manager | Manner of departure | Date of vacancy | Incoming manager | Date of appointment | |
|---|---|---|---|---|---|---|
| Warri Wolves | Lawrence Akpokona | fired | end of 2009-10 season | Paul Aigbogun | 2 September 2010 | |
| Kwara United | Justin Tenger | fired | end of 2009-10 season | Kadiri Ikhana | 17 July 2010[6] | |
| Sunshine Stars | Solomon Ogbeide | fired | Aug. 18 2010 | Gbenga Ogunbote | Aug. 18 2010[7] | |
| Gombe United | Ben Duamlong | Resigned | Oct.8 2010 | Bernard Ogbe | Nov. 5 2010[8] | |
| Heartland | Samson Siasia | resigned to take Super Eagles job | Dec. 1 2010 | Lodewijk de Kruif | Feb. 7 2011 | |
| Niger Tornadoes | Ladan Bosso | fired | Nov. 26 2010 | Samson Unuanel (interim) | Nov. 26 2010 | |
| Crown F.C. | Ganiyu Salami | fired | Jan. 22 2011 | Oladunni Oyekale | Jan. 22 2011 | |
| Kano Pillars F.C. | Salisu Yusuf | resigned to become Super Eagles assistant | Jan. 1 2011 | Ladan Bosso[9] | Jan. 23 2011 | |
| Niger Tornadoes | Samson Unuanel | interim period ends | Feb. 6 2011 | Justin Tenger[10] | Feb. 6 2011 | |
| JUTH F.C. | Tunde Abdulrahman | fired | Feb. 17 2011 | Emmanuel Deutsch | Feb. 28 2011 | |
| Ocean Boys F.C. | Larry Eceli | fired | May 20, 2011 | Samson Unuanel[11] | May 20, 2011 | |
| Bukola Babes F.C. | Festus Allen | suspended/resigned | June 8, 2011 | Kabiru Sulaiman[12] | June 8, 2011 |