| Competition: | Eerste Divisie |
| Season: | 2010–11 |
| Winners: | RKC Waalwijk |
| Promoted: | RKC Waalwijk |
| Relegated: | none |
| Promotion To: | Eredivisie |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
The Eerste Divisie 2010–11 was the 55th season of the Eerste Divisie since its establishment in 1956.
The previous year's winners were De Graafschap, who were replaced by last-placed 2009–10 Eredivisie club RKC Waalwijk. The league featured 18 teams, two fewer than its previous season, following the exclusion of HFC Haarlem from professional football and the relegation of FC Oss to the 2010–11 Topklasse. On May 12, 2010 BV Veendam was declared bankrupt due to financial troubles, with FC Oss consequently expected to be readmitted into Eerste Divisie to replace it; however, the verdict was overturned later in June, and the club was thus allowed to play in the season with a reduced budget.
From this season on, the last-placed team would be relegated to the Topklasse, and replaced by the winner of the newly established third tier.
This season also featured the old Almere-based club FC Omniworld under the new denomination of Almere City FC.
| Club | Location | Venue | Capacity | |
|---|---|---|---|---|
| AGOVV Apeldoorn | Apeldoorn | Stadion Berg & Bos | 3,250 | |
| Almere City FC | Almere | Mitsubishi Forklift Stadion | 3,000 | |
| Cambuur | Leeuwarden | Cambuur Stadion | 10,250 | |
| FC Den Bosch | 's-Hertogenbosch | De Vliert | 9,000 | |
| FC Dordrecht | Dordrecht | GN Bouw Stadion | 4,100 | |
| FC Eindhoven | Eindhoven | Jan Louwers Stadion | 4,600 | |
| FC Emmen | Emmen | Univé Stadion | 8,600 | |
| Fortuna Sittard | Sittard | Wagner & Partners Stadion | 12,500 | |
| Go Ahead Eagles | Deventer | Adelaarshorst | 6,700 | |
| Helmond Sport | Helmond | Stadion De Braak | 4,100 | |
| MVV | Maastricht | De Geusselt | 11,026 | |
| RBC | Roosendaal | RBC Stadion | 4,995 | |
| RKC | Waalwijk | Mandemakers Stadion | 7,500 | |
| Sparta Rotterdam | Rotterdam | Het Kasteel | 11,026 | |
| Telstar | Velsen | TATA Steel Stadion | 3,625 | |
| BV Veendam | Veendam | De Langeleegte | 5,290 | |
| FC Volendam | Volendam | Kras Stadion | 6,260 | |
| FC Zwolle | Zwolle | FC Zwolle Stadion | 10,000 |
Excelsior and VVV-Venlo joined the Eerste Divisie-teams for the playoffs, after finishing 16th and 17th in the Eredivisie.
VVV-Venlo and Excelsior will play in 2011–12 Eredivisie.
Koen van der Biezen (Go Ahead Eagles) Danny Schreurs (FC Zwolle)