| Season: | 2010–11 |
| Mgrtitle: | Head Coach |
| Chrtitle: | President |
| League Result: | 17th |
| Cup1 Result: | Fourth round |
| League Topscorer: | David Di Michele (8 goals) |
| Season Topscorer: | David Di Michele (8 goals) |
| Nextseason: | 2011–12 |
The 2010–11 season was Lecce's 102nd in existence. Lecce returned to the top flight of Italian football, for the first time since the 2005–06 season after completing the 2009–10 Serie B season in first place.
Lecce began a pre-season training camp in Tarvisio on July 15.[1]
| Date | Opponents | H / A | Result F – A | Scorers | |
|---|---|---|---|---|---|
| 24 July 2010 | Nazionale Montepaschi | N | 8 – 0 | Corvia (2) 2', 67', Ferrario 13', Mesbah (2) 19', 68', Munari 26', Falcone 70', Vives 75' | |
| 28 July 2010 | Rappresentativa Friuli Venezia Giulia | N | 9 – 0 | Corvia (3) 27', 56', 65', Bergougnoux (2) 37', 45', Munari 44', Giacomazzi 68', Falcone (2) 69', 87' | |
| 1 August 2010 | Tamai | N | 5 – 0 | Rubén Olivera 8', Corvia 10', Mesbah 60', Donati 64', Grossmüller 68' | |
| 4 August 2010 | Triestina | N | 3 – 1 | Mesbah 12', Corvia 77', Giacomazzi 86' | |
| 12 August 20101 | Pisticci | A | 0 – 1 | Grossmüller 40' | |
| 12 August 20101 | Salernitana | N | 1 – 0 | Grossmüller 8' | |
| 22 August 2010 | Valencia | H | 0 – 2 |
1 45 minute matches played during "Memorial Gaetano Michetti".[2]
Lecce will return to Serie A action on August 29. They will start the season away to Milan.
Based on their finish in the 2009-10 Serie B season, Lecce will enter the 2010–11 Coppa Italia in the third round. Their first opponent in the competition will be Serie B club Siena.
|}
| Date | Pos. | Name | From | Fee | |
|---|---|---|---|---|---|
| 2 July 2010 | MF | Rubén Olivera | Peñarol | Free[3] | |
| 22 July 2010 | GK |  Massimiliano Benassi | Perugia | Free[4] | |
| 30 July 2010 | MF | Carlos Grossmüller | Schalke | Free[5] | |
| 4 August 2010 | MF |  Ignacio Piatti | Independiente | Undisclosed[6] |