| Competition: | Tunisian Ligue Professionnelle 1 |
| Season: | 2010–11 |
| Winners: | Espérance de Tunis |
| Relegated: | None (Ligue 1 extended to 16 teams in 2011–12) |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | Espérance de Tunis Etoile du Sahel |
| Continentalcup2: | Confederation Cup |
| Continentalcup2 Qualifiers: | CS Sfaxien Club Africain |
| League Topscorer: | Ahmed Akaïchi (14 goals) |
| Biggest Home Win: | EST 5–0 ST |
| Biggest Away Win: | ASG 1–4 CAB CSHL 1–4 JSK ESHS 1–4 CA |
| Highest Scoring: | EGSG 4–4 CA |
| Matches: | 182 |
| Total Goals: | 405 |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
The 2010–11 Tunisian Ligue Professionnelle 1(Tunisian Professional League) season was the 85th season of top-tier football in Tunisia. The competition began on 24 July 2010, and will conclude on 8 May 2011. The defending champions from the previous season are Espérance Sportive de Tunis. No teams were relegated as Ligue 1 was to be extended to 16 teams starting from the 2011–12 season.
| Clubs | Venue | Capacity | |
|---|---|---|---|
| AS Gabès | 15.000 | ||
| AS Marsa | Stade Abdelaziz Chtioui | 6.000 | |
| Club Africain | El-Menzah stadium | 45.000 | |
| Club Athletique Bizertin | 20.000 | ||
| CS Hammam-Lif | Bou Kornine stadium | 8.000 | |
| Club Sportif Sfaxien | Taïeb Mhiri's stadium | 22.000 | |
| El-Gawafel Sportives de Gafsa | Stade 7 November Gafsa | 12.000 | |
| Espoir Sportif de Hammam-Sousse | BouAli Lahwar stadium | 6.500 | |
| Étoile Sportive du Sahel | Sousse's Olympic stadium | 30.000 | |
| Espérance Sportive de Tunis | Olympic Stadium of Rades | 65.000 | |
| Espérance Sportive de Tunis | El-Menzah stadium | 45.000 | |
| Stade Jlidi | 8.000 | ||
| JS Kairouan | Stade Ali Zouaoui | 15.000 | |
| Olympique de Béja | Boujemaa El-Kemiti stadium | 8.000 | |
| Stade Tunisien | Chedli Zouiten's stadium | 20.000 |
| Rank | Player | Team | Goals | |
|---|---|---|---|---|
| 1 |  Ahmed Akaïchi | Etoile du Sahel | 14 | |
| 2 | Oussama Darragi | Espérance de Tunis | 10 | |
 Danilo Petrolli Bueno | Etoile du Sahel | 10 | ||
| 4 | Ayoub Kramti | EGS Gafsa | 9 | |
| Youssef Msakni | Espérance de Tunis | 9 | ||
| 6 | Heithem Ben Salem | Club Athletique Bizertin | 7 | |
 Michael Eneramo | Espérance de Tunis | 7 | ||
| Slema Kazdeoui | JS Kairouan | 7 | ||
| 9 | Bilel Ben Messaoud | AS Marsa | 6 | |
| Lamjed Chehoudi | Etoile du Sahel | 6 | ||
| Youssef Mouihbi | Club Africain | 6 | ||
| Amir Omrani | EGS Gafsa | 6 | ||
| Chaker Reguiî | ES Zarzis | 6 | ||
| Hamza Younes | CS Sfaxien | 6 | ||
| 15 |  Kari Kari | CS Hammam-Lif | 5 |