| Competition: | First League of the Republika Srpska |
| Season: | 2010–11 |
| Winners: | Kozara 1st First League title |
| Promoted: | Kozara |
| Relegated: | BSK Famos |
| Matches: | 182 |
| Total Goals: | 450 |
| League Topscorer: | Mladen Bojić (11 goals) |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
The 2010–11 First League of the Republika Srpska was the 16th since its establishment.