| Competition: | Cypriot Second Division |
| Season: | 2010–11 |
| Winners: | Aris (4th title) |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
The 2010–11 Cypriot Second Division was the 56th season of the Cypriot second-level football league. Aris Limassol won their 4th title.
Teams promoted to 2010–11 Cypriot First Division
Teams relegated from 2009–10 Cypriot First Division
Teams promoted from 2009–10 Cypriot Third Division
Teams relegated to 2010–11 Cypriot Third Division
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Łukasz Sosin | Aris Limassol | 19 |
| 2 |  Chris Dickson | Nea Salamina | 16 |
| 3 | Janusz Surdykowski | APEP | 15 |
| 4 | Edward Mashinya | Omonia Aradippou | 13 |
| 5 | Milan Belić | Nea Salamina | 10 |
| Aleksejs Koļesņikovs | Othellos Athienou | ||
 Sotiris Vourkou | PAEEK FC | ||
| Marios Neophytou | Akritas Chlorakas | ||
| 6 | Andreas Pittaras | Chalkanoras Idaliou | 9 |
| 7 |  Ricardo Malzoni | Omonia Aradippou | 8 |
| Milton | Akritas Chlorakas | ||
| Costas Elia | Anagennisi Dherynia | ||
| Panayiotis Pontikos | Omonia Aradippou | ||
| 8 |  Papi Kimoto | APEP | 7 |
| Viktors Morozs | Atromitos Yeroskipou | ||
| 9 | Egola Empela | Othellos Athienou | 6 |
| Filippos Filippou | Chalkanoras Idaliou |
Including matches after 26th matchday; Source:[1]