| Season: | 2010–11 |
| Stadium: | Estadio Corona |
| Chrtitle: | President |
| Chairman: |  Alejandro Irarragorri |
| League: | Torneo Apertura Torneo Clausura |
| League Result: | 3rd 9th |
| Cup1: | Apertura Liguilla |
| Cup1 Result: | Runner-up |
| Cup2: | Clausura Liguilla |
| Cup2 Result: | Did not qualify |
| League Topscorer: | Apertura: Christian Benítez (16) Clausura: Christian Benítez (4) Daniel Ludueña (4) Oribe Peralta (4) |
| Season Topscorer: | Christian Benítez (20) |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
The 2010–11 Santos Laguna season was the 64th professional season of Mexico's top-flight football league. The season is split into two tournaments—the Torneo Apertura and the Torneo Clausura—each with identical formats and each contested by the same eighteen teams. Santos Laguna will begin their season on July 24, 2010 against Atlante, Santos Laguna will play their homes games on Saturdays at 7pm local time.
(to Alacranes de Durango)(to San Luis F.C.)(to Albinegros de Orizaba)(to C.F. La Piedad)(to Club Universidad de Guadalajara)(to Club de Gimnasia y Esgrima La Plata)(to Irapuato FC)(to Club Universidad de Guadalajara)(to Club Universidad de Guadalajara)(to Mérida F.C.)(to Chiapas)(to Tiburones Rojos de Veracruz)
Santos Laguna won 2-1 on aggregate
Santos Laguna won 5-4 on aggregate
Monterrey won 5-3 on aggregate
| width=60 | Position | width=60 | Nation | width=150 | Name | width=100 | League | width=150 | Champions League | width=80 | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  | Christian Benítez | |||||||||
| 2. |  | Carlos Quintero | |||||||||
| 3. | | José María Cárdenas | |||||||||
| 4. |  | Daniel Ludueña | |||||||||
| 5. | | Oribe Peralta | |||||||||
| 6. | | Jorge Iván Estrada | |||||||||
| 6. | | José Rodolfo Reyes | |||||||||
| 6. | Rodrigo Ruiz | ||||||||||
| 6. | Own Goals | ||||||||||
| 10. | | Fernando Arce | |||||||||
| 10. | | Carlos Adrián Morales | |||||||||
| 10. | | Juan Pablo Rodríguez | |||||||||
| 13. |  | Felipe Baloy | |||||||||
| 13. | | Juan Carlos Enriquez | |||||||||
| 13. | | Rafael Figueroa | |||||||||
| 13. | | Arnulfo González | |||||||||
| 13. | | Rodolfo Salinas | |||||||||
| 13. | | Francisco Javier Torres | |||||||||
| TOTAL |
As of July 2, 2010[2] *
| width=60 | Position | width=60 | Nation | width=150 | Name | width=80 | Total |
|---|---|---|---|---|---|---|---|
| 1. | | Christian Benítez | |||||
| 1. | | Daniel Ludueña | |||||
| 1. | | Oribe Peralta | |||||
| 4. | | Carlos Darwin Quintero | |||||
| 4. | | Juan Pablo Rodríguez | |||||
| 6. | | Jorge Iván Estrada | |||||
| 6. | | Fernando Arce | |||||
| 6. | | Felipe Baloy | |||||
| 6. | | Rafael Figueroa | |||||
| 6. | | Jaime Toledo | |||||
| TOTAL |