| Club: | América |
| Season: | 2010–11 |
| Stadium: | Estadio Azteca |
| League: | Apertura 2011 |
| League Result: | 4th (Semifinals) |
| League2: | Clausura 2012 |
| League2 Result: | 6th (Quarterfinals) |
| League Topscorer: | Apertura: Vicente Matías Vuoso (8) Clausura: Ángel Reyna (13) |
| Season Topscorer: | Vicente Matías Vuoso (15) |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
| Pattern La1: | _america10111h |
| Pattern B1: | _america1011h |
| Pattern Ra1: | _america1011h |
| Leftarm1: | 000060 |
| Body1: | FFFF00 |
| Rightarm1: | 000060 |
| Shorts1: | FFFF00 |
| Socks1: | FFFF00 |
| Pattern La2: | _america1011a |
| Pattern B2: | _america1011a |
| Pattern Ra2: | _america1011a |
| Leftarm2: | 000060 |
| Body2: | 000060 |
| Rightarm2: | 000060 |
| Shorts2: | 000060 |
| Socks2: | 000060 |
The 2010–11 América season was the 64th professional season of Mexico's top-flight football league. The season is split into two tournaments—the Torneo Apertura and the Torneo Clausura—each with identical formats and each contested by the same eighteen teams. América will begin their season on July 24, 2010 against Pachuca.
}
América won 4-1 on aggregate
| width=60 | Position | width=60 | Nation | width=150 | Name | width=100 | Goals scored |
|---|---|---|---|---|---|---|---|
| 1 |  | Vicente Matías Vuoso | |||||
| 2 | | Daniel Márquez | |||||
| 3 |  | Daniel Montenegro | |||||
| 4 | Vicente Sánchez | ||||||
| 5 | | Enrique Esqueda | |||||
| 5 | | Miguel Layún | |||||
| TOTAL |
Morelia won 5–3 on aggregate
| width=60 | Position | width=60 | Nation | width=150 | Name | width=100 | Goals scored |
|---|---|---|---|---|---|---|---|
| 1. | | Ángel Reyna | |||||
| 2. | | Vicente Matías Vuoso | |||||
| 3. | Vicente Sánchez | ||||||
| 4 | | Daniel Márquez | |||||
| 4 | | Daniel Montenegro | |||||
| 4 |  | Aquivaldo Mosquera | |||||
| 4 | | Diego Antonio Reyes | |||||
| 8 | Nicolás Olivera | ||||||
| TOTAL |